Objective   To compare the efficacy of percutaneous poking reduction and fixation with open reduction by internal fixation for Sanders type Ⅲ calcaneal fractures.Methods   A total of 90 patients with Sanders type Ⅲcalcaneal fractures treated in the Xinyu People's Hospital from April 2020 to April 2024 were prospectively selected.Patients were randomly assigned to control group (open reduction internal fixation) and study group (percutaneous poking reduction and fixation),with 45 cases per group.They were postoperatively followed up for 1 year.Postoperative excellent-good rate,Bohler's angle,Gissane's angle,surgical metrics,and complications were compared.Results   Postoperative excellent-good rates(88.89% VS 86.67%),and preoperative and postoperative Bohler's angle and Gissane's angle were comparable between groups (all P>0.05).Postoperative Bohler's and Gissane's angles were significantly elevated in both groups compared to preoperative values.The study group demonstrated significantly shorter operative time,less intraoperative bleeding,smaller incisions,and shorter hospitalization than the control group,along with a lower complication rate (4.44% VS 20.00%) (all P<0.05).Conclusion   Both techniques achieve favorable outcomes and functional recovery,while percutaneous poking reduction and fixation demonstrates superior surgical metrics,fewer complications,and enhanced patient recovery potential.

Objective   To explore the clinical efficacy of Sancao Lidan Decoction in treating cholecystitis of liver-gallbladder damp-heat type.Methods   A total of 82 patients with cholecystitis of liver-gallbladder damp-heat type treated in the Dancheng County Hospital of TCM from May 2023 to May 2024 were selected as the research objects.They were divided into the study group(n=41,receiving basic treatment plus Sancao Lidan Decoction) and control group(n=41,receiving basic treatment) according to different treatment methods.The treatment effects and adverse events of the two groups were compared.The traditional Chinese medicine(TCM) syndrome scores,imaging indicators,and serum indicators (total bile acid[TBA],aspartate aminotransferase[AST],gallbladder contractile function,gallbladder wall thickness) before and after treatment,and inflammatory indicators (tumor necrosis factor-α[TNF-α],interleukin-8 [IL-8],interleukin-6[IL-6]) were compared.Results   After 6 weeks of treatment,the total effective rate in the study group was significantly higher than that in the control group (92.68% VS 63.41%,P<0.05).After 6 weeks of treatment,the scores for TCM symptoms,such as bitter taste in the mouth,dry mouth,right flank pain,abdominal distension,and heavy body feeling and fatigue were significantly lower in the study group than the control group(P<0.05).After 6 weeks of treatment,the levels of TBA,gallbladder wall thickness,and AST in the study group were significantly lower than those in the control group,while the gallbladder contraction function was highe(P<0.05).After 6 weeks of treatment,the levels of serum TNF-α,IL-8,and IL-6 in the study group were significantly lower than those in the control group(P<0.05).There was no significant difference in the incidence of adverse events between the study group and the control group (9.76% VS 4.88%,P>0.05).Conclusion   For patients with cholecystitis of liver-gallbladder damp-heat type,Sancao Lidan Decoction can improve treatment efficacy and imaging indicators,reduce inflammatory response,and promote rapid recovery.

Objective   To explore the application value of suspension techniques combined with functional training in the rehabilitation of staff for special services with knee joint injuries.Methods   A total of 110 patients with knee joint injuries treated from December 2023 to December 2024 were selected.They were randomly divided into two groups, each consisting of 55 patients.Patients in the control group received routine care,while those in the observation group underwent suspension techniques combined with functional training.Knee function, pain level and quality of life before and after treatment were compared between groups.Results   Before interventions,there were no significant differences in the scores of pain, function,range of motion,muscle strength, flexion deformation,and stability between the two groups(all P>0.05).After interventions,the HSS scores of the observation group were higher than those of the control group, and the differences were statistically significant(P<0.05).Before interventions,there was no difference in the numerical rating scale(NRS) scores between the two groups(P>0.05).NRS score after interventions was significantly lower in the observation group than the control group([2.11±0.24]points VS [4.08±0.23]points, P<0.001).The score of quality of life before interventions was comparable between group(P=0.104), which, after interventions, was significantly higher in the observation group than the control group(t=68.773,P<0.001).Conclusion   The combination of suspension techniques and functional training is effective in treating knee joint injuries.It not only significantly improves knee joint function but also helps to alleviate pain and enhance quality of life,making it a recommended approach.

Objective   Based on the mechanisms of Qi and Jin injuries,this study investigated the clinical efficacy of traditional Chinese medicine Shengmai Decoctionin treating gout induced by exercise fatigue.Methods   A total of 132 gout patients induced by exercise fatigue from April 2020 to December 2024 were selected and randomly divided into the control group(65 cases) and study group(67 cases) using the envelope method.Patients in both groups were treated with colchicine and meloxicam,and those in the study group were additionally given oral Shengmai Decoction.The total effective rate,pain severity score,pain duration,fatigue score,and changes in blood uric acid and creatine kinase levels were compared between groups.Results   After treatment,the total effective rate of the study group was significantly higher than that of the control group,and the duration of pain was significantly shorter than that of the control group ([48.95±8.74]h VS [56.32±9.05]h,P<0.05).The scores of pain degree ([1.65±0.61]points VS [2.38±0.76]points) and fatigue degree ([25.45±10.83]points VS [35.69±11.02]points) were significantly lower in the study group than the control group(P<0.05).Blood uric acid ([365.83±64.25]μmmoL/L VS [423.75±69.38]μmmoL/L) and creatine kinase ([172.41±44.63]U/L VS [285.36±59.45]U/L) were significantly lower in the study group than the control group (P<0.05).Conclusion   Qi and Jin injuries are the early pathogenesis of gout attacks after exercise fatigue,and traditional Chinese medicine Shengmai Decoction has shown good clinical efficacy in treating them.

Objective   To explore the impact of gut microbiota imbalance on the prognosis of decompensated liver cirrhosis.Methods   A total of 100 patients with decompensated liver cirrhosis in the Third People's Hospital of Zhengzhou from June 2021 to June 2024 were selected as the study group.Routine treatment was given to all patients upon admission,and the abundances of gut microbiota(Bifidobacterium,Lactobacillus,Escherichia coli,Enterococcus) were measured before treatment.Additionally,100 patients with liver cirrhosis compensation and 100 healthy individuals who underwent physical examinations during the same period were included as control group 1 and control group 2,respectively.The gut microbiota of the three groups was compared.After 6 months of follow-up,patients were divided into the good prognosis group and poor prognosis group based on their survival status.Baseline data and gut microbiota counts were compared between the two groups,and Cox regression analysis was used to determine the relationship between gut microbiota and the prognosis of decompensated liver cirrhosis.The receiver operating characteristic(ROC) curve was drawn,analyzing the value of gut microbiota imbalance in predicting the prognosis of decompensated liver cirrhosis.Results   The abundances of Bifidobacterium and Lactobacillus in the study group were significantly lower than the control group 1,and those in the control group 1 were significantly lower than the control group 2.The abundances of Escherichia coli and Enterococcus in the study group were significantly higher than the control group 1,and those in the control group 1 were significantly higher than the control group 2(P<0.05).During the 6-month follow-up period,14 out of 100 patients in the study group died,accounting for 14.00% (14/100).The Child-Pugh grading,model of end-stage liver disease(MELD) score,and proportion of combined malnutrition in the poor prognosis group were significantly different from those in the good prognosis group(P<0.05).The abundances of Bifidobacterium and Lactobacillus in the good prognosis group were significantly higher than the poor prognosis group,while the abundances of Escherichia coli and Enterococcus were significantly lower than the poor prognosis group(P<0.05).According to Cox regression analysis,Child-Pugh grading,MELD score,combined malnutrition,Bifidobacterium,Lactobacillus,Escherichia coli,and Enterococcus were significantly correlated with the prognosis of decompensated cirrhosis(P<0.05).ROC curveshowed that the area under the curve(AUC) of abundances of Bifidobacterium,Lactobacillus,Escherichia coli,and Enterococcus in predicting the prognosis of decompensated liver cirrhosis alone or in combination was all greater than 0.7,which had certain predictive value,and the combined predictive value was higher.Conclusion  Patients with decompensated liver cirrhosis have a higher probability of experiencing gut microbiota imbalance,and gut microbiota imbalance can increase the risk of poor prognosis in patients with decompensated cirrhosis,and can predict patient prognosis to some extent.

Objective   To analyze the comprehensive rehabilitation effect of Dandong Wulongbei Hot Spring combined with Tai-Chi therapy on hypertension patients.Methods   A total of 254 hypertension patients who participated in the rehabilitation in Wulongbei Sanatorium Area of Dalian Rehabilitation and Sanatorium Center from April 2022 to April 2024 were selected.They were randomly divided into the control group and experimental group using a random number table method,with 127 cases in each group.Patients in both groups were medicated with oral amlodipine tablets,while those in the experimental group were additionally treated with hot spring combined with Tai-Chi therapy.Blood pressure levels,anxiety scores,body mass index(BMI),and sleep latency,sleep duration,subjective sleep quality and use of sleeping medication in the Pittsburgh sleep quality index(PSQI) after 3 months of treatment were compared between groups.Results   There was no significant difference in the pre-treatment blood pressure between groups(P>0.05).After three months of intervention,the systolic blood pressure ([125.61±7.14]mmHg VS [137.65±5.32]mmHg,1 mmHg=0.133 kPa) and diastolic blood pressure ([75.30±4.10]mmHg VS [83.80±3.40]mmHg) in the experimental group were significantly lower than the control group(P<0.05).The self-rating anxiety scale (SAS) score was significantly lower in the experimental group than the control group ([32.19±4.72]points VS [39.29±5.45]points, P<0.05).After interventions,the sleep duration score in the control group was significantly lower than the pre-treatment value ([2.23±0.69]points  VS  [2.72±0.34]points,P<0.05).In the experimental group,post-treatment scores of sleep latency ([1.68±0.19]points VS [2.71±0.46]points),sleep duration ([1.78±0.43]points VS [2.67±0.85]points) and sleep quality ([1.56±0.72]points VS [2.52±0.26]points) were significantly decreased(P<0.05).Post-treatment scores of sleep latency and sleep quality were elevated in the control group,although no significant differences were detected.Post-treatment outcomes were more reduced in the experimental group than the control group(P<0.05).Pre-treatment BMI was comparable between groups(P>0.05),and it was reduced in both groups after treatment,but no significant difference was detected between groups(P>0.05).Dosages of sleep medications after treatment were significantly lower in the experimental group than the control group([4.08±1.43]mg VS [5.35±1.74]mg,P<0.05).Conclusion   Dandong Wulongbei Hot Spring combined with Tai-Chi therapy shows pronounced outcome of comprehensive rehabilitation of hypertension.

Objective   To investigate the effect of one-piece ultrasonic concentric puncture in percutaneous nephrolithotomy(PCNL).Methods   A total of 120 patients with upper urinary tract stones who received PCNL in Fuzhou Dongxiang District People's Hospital from January 2024 to March 2025 were selected.They were randomly divided into two groups with 60 cases in each group according to random number table method.Non-concentric puncture was performed in the control group,and one-piece ultrasound concentric puncture was performed in the study group.The perioperative indexes,hemostasis under blood transfusion and intervention,puncture accuracy,puncture time and postoperative complications were compared between the two groups.Results   The operation time ([27.44±4.36]min VS [37.25±4.51]min) and the total hospital stay ([4.03±1.06]d VS [5.12±1.12]d) of the study group were both significantly shorter than those of the control group(P<0.05).Postoperative blood loss within 24 h ([9.55±2.12]g/L VS [13.35±2.62]g/L) and intraoperative blood loss ([9.55±1.65]mL VS [16.25±2.35]mL) were significantly less in the study group than those of the control group(P<0.05).Blood transfusion treatment and hemostasis under intervention were not reported in the study group,showing no significant differences than the control group (3.33% and 1.67%,respectively),P>0.05.The one-time puncture success rate (90.00% VS 75.00%) and the total puncture success rate (100% VS 90.00%) of the study group were significantly higher than those of the control group(P<0.05).Significantly shorter duration of puncture ([4.81±0.66]min VS [6.25±1.21]min) and lower incidence of postoperative complications (5.00% VS 16.67%) were detected in the study group than the control group(P<0.05).Conclusion   One-piece ultrasound concentric puncture during PCNL operation can reduce blood loss,improve puncture accuracy,shorten puncture time,reduce the incidence of postoperative complications and promote rehabilitation.

Objective   To evaluate the accuracy of the non-contact vital sign monitoring device.Methods   The research on the monitoring of human vital signs by contact vital signs detection equipment such as electrocardiogram(ECG) monitor,smart bracelet or respiration monitor and radar was searched in the Cochrane Library,PubMed,Web of Science,Embase,SinoMed,China National Knowledge Infrastructure (CNKI),Wanfang Database and Vip.com from establishing the databases to October 2024.A meta-analysis was performed using Stata 17.0 software.Results   A total of 21 articles with 328 subjects were included.The results of meta-analysis showed no significant differences between radar monitoring and ECG monitoring in the heart rate (standardized mean difference [SMD]=0.05,95%CI[-0.11,0.21],P=0.705) and respiratory rate (SMD=0.10,95%CI[-0.33,0.14],P=0.755).However,subgroup analysis showed that a Frequency Modulated Continuous Wave (FMCW) radar had a more accurate measurement performance than Continuous Wave (CW) radar and Ultra Wideband (UWB) radar.All radar measurement performance was best at about 1 m away from the target,and among many radar frequencies,77 GHz for heart rate and respiratory rate monitoring was the most accurate.Conclusion   There is no significant difference between contact vital signs monitoring equipment and radar in the monitoring of heart rate and respiratory rate,but FMCW radar is superior in accuracy.The most accurate data are achieved when all types of radars are 1 m away from the subjects,and the optimal radar frequency is at 77 GHz.

Hot springs serve as a pivotal avenue for human exploitation of geothermal resources.Their distinctive physical and chemical properties exhibit significant comprehensive benefits in the aspects of power generation,heating,agriculture,daily life and production,tourism,health,and wellness.Hot springs are strategic resource imbued with natural,economic,health,and cultural significance.China has various hot spring resources,with a broad distribution and significant economic value.Mastering the distribution of hot spring resources in China,understanding the mechanisms,main effects,discomfort and prevention of hot spring health care,and looking forward to the development trend of hot spring health care contribute to better development and use of hot spring resources.It also favors regional economic development,the implementation of the Healthy China Action,and harmonious coexistence between man and nature.Hot spring healthcare presents novel treatment alternatives for numerous diseases.As a non-pharmaceutical therapy,hot spring is developed towards differentiation and personalization.The development and utilization of hot spring resources can start from formulating reasonable industrial plans,improving public awareness,enhancing the added value and competitiveness of the hot spring industry,driving the development of related industries,and exploring and inheriting Chinese hot spring culture.

With the advancement of the information and digital waves,digital health,as a product of the deep integration of information technology and medical and health care,has developed rapidly,and the importance of digital health literacy has become increasingly prominent.This article,through a systematic review of relevant literature,explores the current situation of digital health literacy among Chinese residents and its influencing factors.At present,the gap in digital health literacy between urban and rural areas in China is gradually narrowing,but there are still regional and population differences.The digital health literacy level of urban residents is generally higher than that of rural residents.Personal factors(such as age,family situation,job differences,educational attainment and economic level),social environmental factors(such as medical security conditions and regional economic and medical information differences),as well as digital resource factors(including the accessibility of digital resources and residents' attitudes towards digital health information) all have a significant impact on digital health literacy.In the future,multi-center,large-sample cross-sectional surveys and longitudinal studies need to be carried out to comprehensively assess residents' digital health literacy,and based on this,targeted intervention strategies should be developed to enhance the digital health literacy level of the entire population.

Objective   To analyze the current state,primary areas of interest,and emerging trends in pressure injury research,both domestically and internationally over the past decade,thus providing references for clinical nursing practice.Methods   Publications about pressure injuries from January 2013 to December 2023 were systematically searched in the China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform,VIP Information Chinese Journal Service Platform and Web of Science.CiteSpace version 6.2.R3 software was used to conduct a visualization analysis including authors,institutions,countries,and keywords.Co-occurrence maps for authors,institutions,and countries,as well as co-occurrence,clustering,time zone,and burst word maps for keywords were generated.Results   A total of 5 152 Chinese-language articles and 4 178 English-language articles about pressure injury were searched.The results indicated a consistent increase in publication volume both nationally and internationally since 2013.The domestic publication trend displayed an inverted "V" shape,characterized by an initial increase followed by a subsequent decline,while the international trend revealed a steady upward trajectory.The primary research focal points,both domestically and internationally,encompassed the early identification of risk factors for pressure injuries,a widely acknowledged area of inquiry,and precision-customized prevention strategies for pressure injuries,which exhibited varying emphases across domestic and international contexts.The frontiers of research on pressure injuries were continually evolving,necessitating increased attention to orthopedics and innovative dressing materials.Conclusion   The research on pressure injuries both nationally and internationally,indicate a general increase in its prevalence.It is essential for clinical nursing personnel to incorporate contemporary research trends to formulate targeted prevention strategies for pressure injuries.Furthermore,they should become acquainted with the utilization of innovative wound dressings to reduce the risk of these injuries.

Patients with chronic kidney disease(CKD) progressing to end-stage renal disease rely on maintenance hemodialysis(MHD) for survival.However,long-term dialysis is often accompanied by multidimensional functional decline,including muscle atrophy,reduced cardiopulmonary function,and psychological disorders,severely impairing quality of life.This study systematically elucidates the mechanisms of a functionally stratified,stepwise exercise intervention in delaying functional decline among MHD patients and establishes a standardized clinical practice pathway.Using tools such as the modified Barthel index(MBI),6-minute walk test,and grip strength test,patients are stratified into three functional tiers:bedridden,semi-bedridden,and self-care.Tailored exercise prescriptions are then implemented:bedridden patients receive active/passive joint mobilization and respiratory training to prevent pressure ulcers and contractures;semi-bedridden patients undergo balance and transfer training to restore basic mobility;self-care patients engage in aerobic and resistance exercises to mitigate sarcopenia and cognitive decline.Evidence demonstrates that this stepwise intervention significantly enhances muscle mass and strength(via resistance training),improves cardiopulmonary endurance and metabolic regulation(via aerobic exercise),and alleviates anxiety and depression by modulating neurotransmitter release(e.g.,endorphins) and cerebral blood flow,thereby disrupting the "fatigue-reduced activity-functional decline" vicious cycle.The protocol integrates physiological and psychological interventions,emphasizing dynamic assessments and adaptive strategies(e.g.,adjusting exercise prescriptions every 3-6 months),optimizes exercise timing and intensity relative to dialysis cycles,and ensures safety and efficacy.Future multicenter,long-term studies are warranted to validate cost-effectiveness and broader applicability,providing evidence-based strategies for preserving functional capacity in MHD patients.

Objective  To investigate the value of plasma heme oxygenase-1(HO-1),apolipoprotein B(ApoB),homocysteine(Hcy) combined with real-time shear wave elastography(SWE) in evaluating the lesion degree of nonalcoholic fatty liver disease(NAFLD).Methods   A total of 150 patients diagnosed with NAFLD in Henan Provincial People's Hospital from May 2022 to May 2024 were selected as the NAFLD group,and another 150 healthy volunteers were selected as the control group.The parameters of HO-1,ApoB,Hcy and SWE of the two groups were compared,and stratified comparative analysis was performed according to the degree of fatty liver lesions.Results   Serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),triglycerid(TG),and total cholesterol(TC),liver hardness and spleen hardness in the NAFLD group were significantly higher than the control group(P<0.05).The measured values of HO-1,ApoB and Hcy in NAFLD group were significantly higher than the control group(P<0.05).Among 150 NAFLD patients,41 had mild disease,63 had moderate disease,and 46 had severe disease.Serum ALT,AST,TG,TC,LDL-C,liver hardness and spleen hardness in the severe NAFLD group were significantly higher than the moderate and mild groups(P<0.05).Serum HDL-C in the severe group was significantly lower than the mild group(P<0.05).Serum TG and liver hardness in the moderate NAFLD group were significantly higher than the mild NAFLD group(P<0.05).Serum HO-1,ApoB and Hcy values in the severe NAFLD group were significantly higher than the moderate and mild groups(P<0.05).The determination values of HO-1,ApoB and Hcy in the moderate NAFLD group were significantly higher than those the mild NAFLD group(P<0.05).The measured values of serum HO-1,ApoB and Hcy in NAFLD patients were significantly positively correlated with liver stiffness and spleen stiffness(P<0.05).Conclusion   Serum HO-1,ApoB,Hcy,liver hardness and spleen hardness significantly increase in NAFLD patients,and they are closely correlated with the severity of NAFLD.

Objective   To analyze the correlation and clinical significance between the levels of serum secreted frizzled related protein 4(SFRP4),C-X-C chemokine receptor 4(CXCR4),fibrinogen(FIB) and Wagner(Wanger) classification in patients with diabetic foot.Methods   90 patients with diabetic foot admitted to Zhoukou Huaihai Hospital from January 2022 to June 2024 were retrospectively collected as the diabetic foot group,and another 90 patients with simple diabetes during the same period were selected as the simple diabetes group.The general clinical data at admission of the two groups were compared.The levels of serum SFRP4,CXCR4 and FIB in diabetic patients with different Wanger classification were compared and their correlations were analyzed.The influencing factors of diabetic foot in diabetic patients and the diagnostic value of combined detection for diabetic foot was analyzed.Results   The levels of serum SFRP4,CXCR4 and FIB in the diabetic foot group at admission were all higher than those in the simple diabetes group(P<0.05).Comparison of serum SFRP4,CXCR4 and FIB levels in patients with different Wanger classifications showed that patients with grade 0-1 were less than those with grade 2-3 and patients with grade 2-3 were less than those with grade 4-5(P<0.05).The levels of serum SFRP4,CXCR4 and FIB at admission were all positively correlated with the Wanger classification of the patients(P<0.05).The duration of diabetes,transcutaneous oxygen partial pressure,serum SFRP4,CXCR4,and FIB were all related to the occurrence of diabetic foot.After adjustment,serum SFRP4,CXCR4,and FIB were risk factors for diabetic foot in patients(P<0.05).The efficacy of combined diagnosis of diabetic foot by serum SFRP4,CXCR4 and FIB levels at admission was 0.821.Conclusion   The levels of serum SFRP4,CXCR4 and FIB in patients with diabetic foot are significantly increased and positively correlated with the Wanger classification of the patients.All of them are influencing factors for the occurrence of diabetic foot,and it is found that their combined detection has a high application value in diagnosing the occurrence of diabetic foot.

Objective   To explore the effects of high-flow nasal cannula oxygen therapy on cardiopulmonary function,exercise capacity,and biomarkers in patients with chronic obstructive pulmonary disease (COPD) and mild-to-moderate pulmonary hypertension(PH).Methods   Sixty COPD patients with mild-to-moderate PH admitted to the 923rd Hospital of the Joint Logistics Support Force from July 2022 to November 2024 were selected as the subjects.They were randomly divided into the control group and observation group using a random number table method,with 30 cases per group.Patients in the control group received traditional nasal cannula oxygen therapy on the basis of conventional treatment,while those in the observation group received nasal high flow humidified oxygen therapy on the basis of conventional treatment.Vital signs (heart rate [HR],respiratory rate [RR],mean arterial pressure [MAP]),lung function (forced expiratory volume in the first second [FEV1],forced vital capacity [FVC],peak expiratory flow rate [PEFR]),blood gas analysis indicators (partial pressure of arterial oxygen [p(O2)],arterial oxygen saturation [SaO2],partial pressure of arterial carbon dioxide [p(CO2)],exercise capacity (6-minute walking distance[6MWD]),and biomarkers (lactate dehydrogenase[LDH],B-type natriuretic peptide[BNP],troponin I[TnI]) between groups before and after one week of treatment were compared.Results   After one week of treatment,patients in the observation group had significantly higher FEV1([2.92±0.61]L VS [2.47±0.57]L),FVC([3.46±0.86]L VS [2.96±0.74]L) and PEFR([4.04±0.72]L/s VS [3.31±0.59]L/s) than the control group(P<0.05).Patients in the observation group had significantly higher p(O2) ([70.21±6.45]mmHg VS [64.34±6.04]mmHg,1 mmHg=0.133 kPa),SaO2 ([95.51±6.24]% VS [92.09±6.03]%),and p(CO2) ([47.74±4.12]mmHg VS [51.24±4.53]mmHg) than the control group(P<0.05).There were no significant differences in the HR,RR and MAP between the two groups (t=0.085,1.027,and 0.169,respectively,all P>0.05).The 6MWD of the observation group was significantly longer than that of the control group(P<0.05).LDH,BNP and TnI were significantly lower in the observation group than the control group(P<0.05).Conclusion   Nasal high flow humidified oxygen therapy can improve lung function,blood gas analysis indicators,increase 6MWD,and reduce LDH,BNP and TnI in COPD patients with mild-to-moderate PH.

Rapid analgesia plays a crucial role in battlefield treatment and is of vital importance for maintaining the stability of the vital signs of the wounded.After trauma occurs, the vital signs of the injured often fluctuate due to pain.Timely pain relief can effectively prevent the deterioration of vital signs caused by pain.Meanwhile,pain is one of the important inducing factors of post-traumatic stress disorder (PTSD),and rapid analgesia can significantly reduce the risk of PTSD occurrence.In addition,rapid and effective analgesia can enable the wounded to better cooperate with treatment and improve the efficiency of battlefield treatment.This article provides an in-depth and systematic review of the neurobiological mechanisms of pain,analyzing the principles of pain generation from aspects such as neural conduction pathways.Meanwhile, the biochemical assessment indicators of war trauma pain,such as inflammatory factors, and their association with pain are elaborated in detail.It also combines advanced analgesic drugs and technologies of modern medicine,as well as characteristic treatment methods of traditional Chinese medicine such as acupuncture and herbal medicine,to comprehensively explore the application prospects of multimodal analgesic strategies in the treatment of war trauma pain.By integrating existing research results and clinical practice experience, the aim is to provide solid theoretical support and practical guidance for rapid analgesia of war trauma.

Objective   To explore and summarize the research status and development trend of military physical training in China.Methods   A total of 257 articles on the theme of military physical training were retrieved on the China National Knowledge Infrastructure(CNKI) (1994-2024),and the map was drawn by CiteSpace software.Authors,research institutions,keyword co-occurrence,keyword clustering,keyword prominence and timeline map of the published articles in the field of military physical training research in the past 30 years were visually analyzed.Results   In terms of the number of publications,the trend of the number of publications in the field of military physical training research in China was mainly divided into three stages: the slow increase stage(1994-2005),the rapid increase stage(2006-2016),and the gradual decline stage(2017-2024).In terms of research authors and institutions,scientific research cooperation between authors and institutions was insufficient,and no core author group has been formed.In terms of research hotspots,it mainly included the exploration of physical training methods and models,the physiological effects of various groups of military personnel and training on the body,etc.With the deepening of the research in the field of military physical training,different research hotspots have also emerged in different periods,and keywords such as prevention and treatment of training injuries,actual combat,and informatization have also become research hotspots in this field in recent years.Conclusion   In the future research,it is suggested that more academic exchanges should be carried out between scholars and institutions,thus strengthening cooperation with local sports colleges and related scientific research institutions,promoting the cross-integration of related disciplines and military physical training,actively learning from advanced training models and methods,and accelerating the development of military physical training research field.It aims to achieve better improvement of the scientific level of military physical training,physical quality of military personnel,and combat effectiveness.

Objective   To explore the influencing factors for coagulation dysfunction in elderly patients with severe pneumonia complicated by sepsis,and to create a Logistic regression prediction model to analyze its predictive value for the occurrence of coagulation dysfunction,providing a reference for formulating clinical intervention plans.Methods   A total of 118 elderly patients with severe pneumonia accompanied by sepsis treated in the Second Affiliated Hospital of Zhengzhou University from January 2023 to January 2025 were selected for a retrospective analysis.These patients were categorized into the occurrence group and non-occurrence group based on whether they developed coagulation dysfunction within 72 hours after admission.The clinical data of the two groups were compared,and the influencing factors for coagulation dysfunction were analyzed.A risk prediction model was constructed,and its calibration and discrimination were verified.Results   Among 118 elderly patients with severe pneumonia accompanied by sepsis,the incidence of coagulation dysfunction within 72 hours after admission was 66.10%(78/118).The patients of occurrence group had significantly older age,longer time from onset to admission,longer duration of severe pneumonia,higher acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ) scores,D-dimer,blood lactate,serum procalcitonin(PCT),and interleukin-6(IL-6) than the non-occurrence group (P<0.05).Age,time from onset to admission,APACHE Ⅱ score,D-dimer,blood lactate,serum PCT,IL-6 levels were independent risk factors for the occurrence of coagulation dysfunction(P<0.05).Logit(P)=-5.224+0.239×age+0.313×APACHE Ⅱ score+0.138×time from onset to admission+

0.300×PCT+0.192×blood lactate+0.330×IL-6+0.233×D-Dimer.The area under the curve(AUC) of the Logistic regression prediction model for the occurrence of coagulation dysfunction was 0.924 (95%CI:0.861~0.965),with a sensitivity of 84.62% and a specificity of 90.00%.The Hosmer-Lemeshow test obtained the value χ2=7.556 ,P=0.092.The internal validation method revealed a mean absolute error(MAE) of 0.012 and a mean squared error(MSE) of 0.000 15.The Bootstrap test indicated a C-index of 0.585(95%CI:0.485~0.633).Conclusion   Age,time from onset to admission,APACHE Ⅱ score,D-dimer,blood lactate,serum PCT,IL-6 levels are independent risk factors for the occurrence of coagulation dysfunction in elderly patients with severe pneumonia accompanied by sepsis.A Logistic regression prediction model constructed based on these risk factors has good predictive value for the occurrence of coagulation dysfunction and is helpful in guiding the development of individualized treatment plans in clinical practice to reduce the occurrence of coagulation dysfunction.

Abstract: Objective: Taking pilots as the research object, hot spring water therapy and modified Baduanjin were given during their core muscle group exercise, and the effects of the two therapies on strengthening the core muscle group exercise of pilots were further analyzed. Method: From January 2023 to January 2024, 68 pilots who needed to strengthen their core muscle function were selected for the study and randomly divided into double-blind groups. Control group, regular core muscle group exercise, 34 cases. Observation group, consisting of 34 cases, underwent routine core muscle group exercise and modified Eight Section Brocade in hot spring water. Comprehensively analyze the level of physical exertion, anxiety, and pain in two groups of patients before and after intervention. Before the intervention, there was no significant difference in the degree of exercise difficulty between the two pilots, P>0.05; after the intervention, the observation group had less exercise difficulty, P<0.05. Before the intervention, there was no significant difference in waist function between the two groups of pilots, P>0.05; after the intervention, the waist function of the observation group pilots was better, P<0.05. Before the intervention, there was no significant difference in the comparison of multifidus muscle between the two groups of pilots, P>0.05; after the intervention, the thickness of multifidus muscle in the observation group patients was better, P<0.05. Conclusion: Improving the Eight Section Brocade in warm water during core muscle training for shipborne pilots has a significant effect. Specifically, this is reflected in the fact that after receiving the modified Eight Section Brocade exercise, the patient's level of physical exertion decreased, their anxiety and psychological state improved, and their pain level decreased. It is recommended.

Objective   To investigate the association between the triglyceride glucose-body mass index (TyG-BMI) and the risk of non-alcoholic fatty liver disease(NAFLD) among military aircrews.Methods   A retrospective analysis was conducted among 1 430 aircrew personnel who underwent health examinations at a sanatorium from January 2022 to December 2024.NAFLD was diagnosed using high-resolution color Doppler ultrasound,and the overall detection rate was calculated.Participants were stratified into quartiles(Q1-Q4) based on TyG-BMI values.Metabolic parameters were compared between NAFLD and non-NAFLD groups,and multivariate logistic regression analysis was performed to identify independent risk factors.The predictive value of metabolic indicators was evaluated using receiver operating characteristic(ROC) curve analysis.Results   The overall NAFLD detection rate was 21.12% (302/1 430),and its prevalence significantly increased with advancing age (trend test,P<0.001).Individuals in the NAFLD group exhibited significantly higher levels of fasting plasma glucose(FPG),triglycerides(TG),total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),uric acid(UA),and body mass index(BMI) compared to the non-NAFLD group (all P<0.001).Multivariate analysis identified that UA (OR=1.003,95% CI:1.001~1.005),TC (OR=1.494,95%CI: 1.224~1.823),and TyG-BMI (OR=1.045,95%CI:1.036~1.054) were independent risk factors for NAFLD,while high-density lipoprotein cholesterol(HDL-C) showed a protective effect(OR=0.459,95%CI:0.256~0.823).ROC curve analysis revealed that TyG-BMI had the highest predictive value(AUC=0.821,95% CI: 0.791~0.851),with an optimal cutoff value of 211.11(sensitivity=79.0%,specificity=71.0%).Conclusion   NAFLD prevalence is notably high among military aircrews and positively correlates with age.TyG-BMI,by integrating parameters of glucose-lipid metabolism and body composition,serves as a superior screening indicator for NAFLD in aviation medicine.We recommend a TyG-BMI threshold-based stratified management strategy to enhance metabolic health surveillance systems for this occupational population.

Objective   To study and analyze the level of plateau recuperation support after follow-up investigation on the post recuperation effects of plateau officers and soldiers.Methods   In July 2023,a follow-up survey was conducted on 57 convalescent personnel from a plateau military unit,who were divided into three groups:15 at an altitude of 3 000~4 900 meters,23 at an altitude of 5 000~5 300 meters,and 19 at an altitude of 5 380~5 426 meters.Questionnaire surveys,testing,and follow-up studies were conducted to analyze the effects of recuperation on plateau officers and soldiers.Results   Special treatment for recuperation personnel accounted for 54.4%,while health and specialized treatment accounted for 42.1%.The pulse,respiration,systolic blood pressure,and diastolic blood pressure of each group were all within the normal range,and the oxygen saturation was low,with an average of(90.95±6.50)%.Plateau officers and soldiers had a great demand for recuperation and high satisfaction,and supported special treatment arrangements for personnel above 4 000 meters in altitude.The effects of rehabilitation for plateau officers and soldiers were significant,which were reflected in the reduction of symptoms of altitude sickness,and significant increase in understanding of plateau conditions and personal health maintenance.After recuperation,the life style was improved,the psychological condition was adjusted and the influence of illness on work was reduced.Conclusion   Plateau officers and soldiers have great demand for convalescence,and the after-effect of recuperation is obvious.In the future,we can strengthen the implementation of the plateau recuperation security system,carry out research on the plateau recuperation security measures,further improve the after-effect of recuperation,and provide a strong guarantee for improving the military operation ability and health maintenance of officers and soldiers on the plateau.

Objective   To understand the difference in the cognition of gout diagnosis and treatment between doctors in a sanatorium and a tertiary hospital in Tengchong City,and its influencing factors.Methods   From August to November 2024,personal information of general practitioners and internal medicine doctors was collected from one military sanatorium and two tertiary grade A hospitals in Tengchong City.A questionnaire survey was conducted on the awareness of gout among the respondents,and the data were analyzed.Chi-square test was used to analyze the differences in the awareness of gout diagnostic criteria among doctors from the two types of medical institutions and the influencing factors.Results   The education level(χ2=26.83,P<0.01) and professional title(χ2=8.185,P<0.01) of doctors in Tengchong military sanatorium were significantly lower than those in the tertiary hospitals.The average cases of hyperuricemia(χ2=18.884,P<0.01) and gout(χ2=14.149,P<0.01) admitted by doctors in military sanatorium were significantly lower than those in the tertiary hospitals.The overall awareness rate of gout diagnosis and treatment was generally low(χ2=14.913,P<0.05),especially the choice of treatment and medication for acute gout was not ideal.Conclusion   Doctors in Tengchong City have a certain blind spot in the diagnosis and treatment of gout.Notably,the military sanatorium doctors can not treat the acute stage of gout timely and correctly,and choose a reasonable comprehensive treatment plan.In order to improve the gout diagnosis and treatment ability of doctors in Tengchong City,we should not only pay attention to the academic qualifications of doctors,but also increase their practice opportunities in professional fields.

Objective   To detect the prevalence and influencing factors of hyperuricemia in seafarers at Chongqing Port,thus providing references for the formulation of targeted intervention measures.Methods   A cross-sectional study method was adopted,with 1 366 seafarers who underwent health examinations at Chongqing Port in 2024 as the research objects.Univariate and multivariate Logistic regression analyses were used to discuss the risk factors of hyperuricemia.Results   The total detection rate of hyperuricemia was 34.63%(473/1 366),which was significantly higher than that of the general population.The average body mass index(BMI) of male seafarers(24.13 kg/m2) exceeded the normal range,and the proportion of overweight/obese seafarers was 47.36%.The risk of hyperuricemia was significantly higher in the overweight group(OR=2.099,95%CI:1.591-2.769) and the obese group(OR=2.297,95%CI:1.507-3.500).The prevalence was negatively correlated with age(all P<0.05),and the prevalence of young seafarers(18-25 years old) was the highest(38.89%).Fatty liver(OR=1.437,P=0.023) and hypertension(OR=1.564,P=0.004) were independent risk factors.The risk of those with a preference for high-calorie foods increased marginally(OR=1.518,P=0.059),while the risk of those with long-term overwork decreased(OR=0.420,P=0.007).Conclusion   The prevalence of hyperuricemia among seafarers at Chongqing Port is high,which is closely related to youth,overweight/obesity,metabolic diseases and poor diet.It is recommended that multiple departments cooperate to reduce the risk of disease,ensure the health of seafarers and promote the sustainable development of the shipping industry.

Objective   To analyze the influenza surveillance data from 2023 to 2024 in Nanyang City and to provide evidence for the prevention and control of influenza.Methods   The data of influenza-like illness (ILI) outbreak in Nanyang City from April 2023 to March 2024 in the China Influenza Surveillance Information System were collected,and the epidemic characteristics,population distribution characteristics,and time,gender and age distribution of nucleic acid test results for ILI were analyzed.Results   ILI monitored by the two sentinel hospitals in Nanyang City from 2023 to 2024 accounted for 1.24% of the total number of hospital-visited patients in the same period,with 0.96% in the national sentinel hospitals and 1.58% in the non-national sentinel hospitals (χ2=676.470,P<0.001).In this year,a total of 2 231 ILI samples were detected,and 505 were positive for influenza virus nucleic acid (22.64%),including 332(65.74%) for type A H3N2,158(31.29%) for type B Victoria,and 15(2.97%) for type A H1N1.According to the analysis of samples from different sources,the positive detection rate of outbreaks was the highest (45.00%),which was significantly higher than that of national sentinel hospitals (27.46%) (χ2=5.877,P=0.015).The positive detection rate of national sentinel hospitals was significantly higher than that of non-national hospitals (16.99%)(χ2=34.782,P<0.001).The positive detection rate in 0-4 years old group was the lowest (11.42%),and the positive detection rate in 25-59 years old group was the highest (30.69%).There was a significant difference in the positive detection rate among different age groups (χ2=90.296,P<0.001).The epidemic peak was from October to March of the following year,in which the positive rate was the highest in November(64.29%),and the positive rate gradually decreased from November to March of the following year.Influenza A H3N2 was predominant from October to December,and influenza B Victoria was predominant from January to March.There was a significant difference in the distribution of positive influenza virus subtypes in different months(χ2=398.472,P<0.001).Conclusion   The population is generally susceptible to influenza virus.Health education should be carried out extensively to enhance the public's attention to influenza prevention.Etiological surveillance is recommended to continuously carry out,and the composition of disease prototypes should be timely strengthened,thus providing more scientific bases for the development and use of influenza vaccines.

Objective   To  investigate  the  clinical  effect  of  O-arm  navigation-assisted  spinal  decompression  and bone  grafting  via   a  posterior  approach   combined  with   internal  fixation  in  the  treatment  of  spinal  degenerative diseases. Methods    From  December  2022  to  May  2023, totally   106  patients  with  an  elective  surgery  for  spinal degenerative  diseases  in  Dushan  Hospital  of  Nanyang   City  of  Traditional  Chinese  Medicine  were   selected  and randomly  divided  into  O-arm  group  and  C-arm  group  according  to random number table method, with  53  cases  in each group.Patients in the O-arm group and C-arm group were treated with spinal decompression and bone grafting via  a posterior  approach  combined  with  internal  fixation  assisted  with  O-arm  and  C-arm, respectively. Perioperative indexes, lumbar  function, lumbar  pain   and  complications  were  compared  between  the  two  groups. Results    The hospitalization time([7.23± 1.78]d VS [9.62±2.88]d) and operation time([196.21±36.85]min VS [260.94±68.42]min) of O-arm group were significantly shorter than those of C-arm group(r<0.05).The intraoperative blood loss([76.32±24. 15]mL VS  [ 108.21±28.65]mL)  and  fluoroscopy  times([4.45± 1. 12]times  VS   [ 11.58±2.64]times)  in  the  O-arm  group  were significantly  less  than  those  of  the  C-arm  group(r<0.05). The  accuracy  of  nail  placement  in  O-arm  group  was significantly better than that  in  C-arm  group(r<0.05). There was no  significant  difference between the preoperative Oswestry disability index(ODI) scores and the visual analogue scale(VAS) scores of the lumbar and legs between the two groups(r>0.05).Three months after surgery, ODI scores and VAS scores of lumbar and legs in both groups were significantly lower than those before surgery,and the ODI scores([ 10.54±2. 16]points VS [ 12.66±2.31]points) and VAS scores  of lumbar([2.06±0.64]points  VS  [2.71±0.72]points)  and  legs([1.01±0.35]points  VS  [ 1.33±0.42]points)  in  the O-arm group were significantly lower than those of the C-arm group(r<0.05). There was no significant difference in the total incidence of postoperative complications between the two groups(r>0.05). Conclusion   The  use of O-arm navigation  technology  in  the  operation  of  spinal  degenerative  diseases  can  improve  the  accuracy  of  surgical  nail placement, shorten the operation time,reduce the amount of blood loss and intraoperative fluoroscopy times, alleviate the pain of waist and leg,and improve the function of lumbar spine,which is worthy of clinical popularization.

Objective   To explore the effects of dual task training combined with progressive squat resistance training intervention on motor function and balance ability of patients with Parkinson's disease (PD).Methods   A total of 76 PD patients admitted to the Affiliated Hospital of Jiujiang University of Jiangxi Province from January 2021 to January 2024 were selected and divided,according to a random number table,into a control group of 38 patients who received routine rehabilitation training and a study group of 38 patients who received dual task training combined with progressive squat resistance training.The motor function(Fugl-Meyer assessment scale[FMA]),balance function(Berg balance scale [BBS]),cardiopulmonary endurance(10 min walking test[10 MW]) and cognitive function(Montreal cognitive assessment scale[MoCA]) were compared between the two groups before and after the intervention.Results   After intervention,the scores of upper extremity(53.43±5.02),lower extremity(28.58±2.47) and total score of FMA (82.02±4.13) in the study group were higher than those in the control group (44.72±4.76),(22.05±3.18) and (66.77±4.87).The BBS score (22.82±1.53) was higher than that of the control group (19.57±1.39),and the 10 MW(15.27±6.04)s was shorter than that of the control group (18.56±6.45)s,and the difference was statistically significant(P<0.05).The score of each dimension and total score of MoCA in the study group were higher than those in the control group,and the difference was statistically significant(P<0.05).Conclusion   Dual task training combined with progressive squat resistance training can help improve the motor function,balance function and cognitive function of patients with PD,and improve cardiorespiratory endurance.

Objective   To explore the effects of repetitive transcranial magnetic stimulation (rTMS) based on cognitive remodeling mode on mental status and cognitive function of patients with Alzheimer's disease (AD).Methods   A total of 104 patients with Alzheimer's disease from the First Affiliated Hospital of Henan University from January 2021 to January 2023 were included and divided into two groups according to random number table.Both groups were given comprehensive treatment including drugs,aerobic exercise and cognitive training;52 patients in the control group were given cognitive remodeling mode;52 patients in the observation group were added rTMS.Both groups were treated for 12 weeks continuously and followed up for 24 weeks.Cognitive function,mental status,agitated behavior,neurotransmitter levels and serum inflammatory factors were compared between the two groups.Results   Before intervention,there was no difference of statistical significance in the data between the two groups (P>0.05).After intervention,the score of ADAS-cog (14.05±2.96) of the observation group was lower than that of the control group(18.89±3.40),P<0.05;The score of Montreal cognitive assessment scale (MoCA)(27.96±2.11) was higher than that of the control group (24.03±3.09),P<0.05;The score of mini-mental state examination(MMSE) (25.93±2.54) was higher than that of the control group(19.58±3.01),P<0.05;The score of neuropsychiatric inventory(NPI)(53.10±4.96) was lower than that of the control group(58.05±6.32) ,P<0.05;The score of geriatric depression scale(GDS)(10.28±1.96) was lower than that of the control group(15.25±2.18);The score of Cohen-Mansfield agitation inventory(CMAI)(52.23±7.01) was lower than that of the control group (71.46±6.59);Serum 5-hydroxytryptamine(5-HT)(72.47±5.02)ng/mL was higher than that of the control group (60.02±5.15)ng/mL;Ach(58.68±7.28)nmol/L was higher than that of the control group (45.20±6.12)nmol/L;γ-aminobutyric acid(GAGB) (28.87±0.42)μmol/L was higher than that of the control group (25.20±0.31)μmol/L;Interleukin 6(IL-6)(18.35±3.28)ng/L was lower than that of the control group (29.62±3.69)ng/L;Tumor necrosis factor-α(TNF-α) (22.56±2.84)ng/L was lower than that of

the control group(33.79±3.62)ng/L;Interferon-γ(IFN-γ) (36.85±3.82)ng/L was lower than that of the control group (52.46±4.19)ng/L;T helper cell (Th17) (0.82±0.29)/μL was lower than that of the control group (1.05±0.32)/μL(P<0.05).There was statistical significance in the indicators of each group after intervention compared with before intervention(P<0.05).Conclusion   rTMS combined with cognitive remodeling mode has a significant effect on AD patients,which can effectively improve cognitive function,control agitated behavior and mental status,and promote neural function repair.

Objective   To investigate the effect of rock salt aerosol therapy on the quality of life of pneumoconiosis patients with chronic obstructive pulmonary disease(COPD). Methods   A total  of 186 pneumoconiosis patients with COPD  admitted  in  the  Beidaihe  Sanatorium  of the  Ministry  of Emergency  Management  from  2022  to  2024  were selected  as the  study  objects. The patients were  stratified  according to the  stage  of pneumoconiosis, and  each  group was  subdivided into rock salt therapy group and conventional group by a random principle. The conventional group was given conventional anti-inflammatory,expectorant,airway dilation,pulmonary circulation improvement,anti-fibrosis, nutritional support, etc. The rock salt therapy group was given rock salt aerosol therapy on the basis of conventional treatment.  Interventions   were    performed   one    hour   per    time,  once    a    day,  for    4   weeks.  Before    treatment, 2  weeks  after treatment  and  4  weeks  after treatment, the  self-made  quality  of life  assessment  table  and  the  COPD assessment test(CAT) questionnaire were used to evaluate the pneumoconiosis. The results were statistically analyzed by SPSS 20.0 software. Results   The quality of life  scores for the conventional group before treatment,2 weeks after treatment,and 4 weeks after treatment were (65. 11±4.50)points,(62.91±4. 18)points,and (60. 13±3.85)points,respectively. The  rock  salt  therapy  group  scored  (64.34±5.36)points, (58.42±4.46)points, and  (54. 18±3.85)points, respectively. The differences  in  the  quality  of  life  scores  between  groups  at  various  time  points  after  treatment  were  significantly different (r<0.01). The CAT scores for the conventional group before treatment,2 weeks after treatment, and 4 weeks after treatment were (28.47±3.27)points,(26.40±3.01)points, and (24.24±2.00)points,respectively. The rock salt therapy group  scored  (28.52±3.33)points, (24.30± 1.52)points, and  (22.03± 1. 19)points, respectively. The  differences between the rock salt therapy group and the conventional group at various time points after treatment were significantly different (r<0.01).The total effective rate of the rock salt therapy group was significantly higher than that of the  conventional group (75.56% VS 64.58%,r<0.05). Conclusion   Rock  salt  aerosol therapy  can improve the clinical symptoms and quality  of life  of pneumoconiosis patients  combined with  COPD, and its  efficacy is  significantly better than that of conventional internal medicine treatment alone.

目的：探讨新编八段锦联合自拟降脂茶在痰湿内阻型高脂血症（Hyperlipidemia, HLP）中的疗效。方法：选择南昌市洪都中医院2021年4月至2023年5月收治的HLP患者，按随机数字表将80例分为两组，各40例。两组均给予常规治疗。对照组给予阿托伐他汀钙片，研究组给予新编八段锦联合自拟降脂茶，两组均连续治疗12周。对比两组临床疗效、血脂指标[总胆固醇（Total Cholesterol, TC）、三酰甘油（Triglyceride, TG）、高密度脂蛋白胆固醇（High-Density Lipoprotein Cholesterol, HDL-C）、低密度脂蛋白胆固醇（Low-Density Lipoprotein Cholesterol, LDL-C）]、体质指数以及应用安全性。结果：研究组治疗后TC、TG、LDL-C水平分别为（5.33±0.77）mol/L、（1.76±0.44）mmol/L、（1.88±0.47）mmol/L均低于对照组的（5.82±1.02）mmol/L、（2.77±0.54）mmol/L、（2.56±0.67）mmol/L，HDL-C水平为（1.52±0.28）mmol/L，高于对照组的（1.24±0.26）mmol/L，差异有统计学意义（P<0.05）；研究组治疗后体质指数水平为（23.19±2.42）kg/m²，低于对照组的（24.88±2.60）kg/m²，差异无统计学意义（P>0.05）；两组不良反应发生率相近（P>0.05）。结论：新编八段锦联合自拟降脂茶在痰湿内阻型HLP中疗效显著，可有效改善患者血脂，减轻体质指数，且具有良好的应用安全性。

Objective   To  identify the sleep quality and perceived stress levels in military staff for special service. Methods   A total  of 229  military  staff for  special  service at a rehabilitation and recuperation center from April to October  2023 were  selected by  a  convenience  sampling. The  Pittsburgh  sleep  quality  index(PSQI)  and  the  Chinese version of the perceived stress scale(CPSS) were used to investigate the sleep quality and the perceived stress level, respectively. Spearman's  rank  correlation  was  used  to  analyze  the  relationship  between  sleep  quality  and  perceived stress, and multiple  linear regression was used to  analyze the  influencing  factors  for perceived  stress. Results   The mean PSQI of military staff for special service was (5.48±3.21)points,with 66(28.82%) cases having a PSQI>7 and the scores of 1 or more for sleep latency and sleep duration.The mean CPSS score was ( 16.34±7.95)points and 14(6. 11%) of  them  had   a  moderate   level  of  perceived  stress. There  was   a  positive   correlation  between   sleep  quality  and perceived  stress. Multiple  linear  regression  analysis  showed  that  daytime  dysfunction  was  an  influencing  factor  for perceived stress among military staff for special service(r<0.001).Conclusion   Military  staff for special service have sleep  problems  and  should  be  concerned. Rehabilitation  and  recuperation  may  be  an  effective  way  to  improve  the quality of sleep and relieve stress among military staff for special service.

Objective   To deeply explore the analgesic mechanism of auricular acupuncture,combine the theory of traditional Chinese medicine with the theory of modern medicine,provide theoretical basis for clinical application,and verify its universality and practicability.Methods   Multiple theoretical perspectives were analyzed such as the theory of meridians and internal organs in traditional Chinese medicine,the theory of modern neuroscience,the theory of body fluids and the theory of holography,and clinical cases of auricular acupuncture treatment for different types of pain were collected and analyzed.Results   The mechanism of auricular acupuncture to relieve pain was supported by multi-dimensional theories,and combined with clinical cases,the complex network of action of auricular acupuncture in pain relief was revealed.Conclusion   Through comprehensive theoretical analysis and clinical practice verification,this study clarified the multiple mechanisms of auricular acupuncture analgesia and its universality and practicability in clinical application.Auricular acupuncture not only provides a new and effective treatment for clinical pain treatment,but also provides a new idea for the modernization of traditional Chinese medicine and the study of integrated Chinese and Western medicine.In the future,the specific mechanism of auricular acupuncture therapy should be further studied,and the treatment plan should be optimized to better serve the majority of pain patients.

Objective   To  investigate the  effects of acupuncture combined with rehabilitation training on pain and motor  function  in  patients  with  chondromalacia  patellae(CMP). Methods    Sixty  patients  with   CMP  admitted  to Luoyang Orthopaedic Hospital from January 2023 to March 2024 were selected as the study objects.According to the random number table,the patients were randomly divided into control group and study group,30 cases each.Patients in both groups were given conventional oral medicine treatment, the control group was given rehabilitation training on this  basis, and  the  study  group  was  given  acupuncture  combined  rehabilitation  training  on  this  basis. The  clinical efficacy  of the  two  groups  was  evaluated  30  days  after  treatment. The  knee  pain  status  of the  two  groups  before treatment, 15 days after treatment and 30 days after treatment (visual analogue pain scale[VAS]) and motor function before  and  after treatment  (Western  Ontario  and McMaster Universities  arthritis  index  scale[WOMAC  scale])  were compared, and the symptom improvement time of the two groups was recorded. Results   Compared with  73.33% of the control group, the total clinical effective rate of the  study group  93.33% was higher(r<0.05). VAS  scores of the control  group  were  lower  than  those  of  the  study  group  after   15  and  30  days  of  treatment, with  difference  of statistical  significance(r<0.05). After  30  days  of  treatment, the  total   score  of  WOMAC  scale  and  scores  of  all dimensions were  decreased  in both  groups(r<0.05), and the  study  group was  even  lower(r<0.05). The time  of knee pain  disappearance, normal  activity  and  patella  grinding  test(- )  in  the  study  group  were  shorter  than  those  in  the control  group, and  the  difference  was  statistically  significant(r<0.05). Conclusion    Combined  use  of  acupuncture therapy on the basis of rehabilitation training can improve the clinical efficacy of CMP patients,their knee pain can significantly be improved,and the knee function and lower limb movement ability can significantly be increased.

Stroke accounts for a high proportion in cardiovascular and cerebrovascular diseases,and aphasia is one of the common complications of stroke.The recovery of aphasia depends on semantic recovery,with directly related to factors of auditory input, visual input, memory retention, etc. In this paper, language rehabilitation therapy, non-invasive intervention, drug   intervention, traditional   Chinese  medicine   intervention   and  music   intervention  with   semantic activation were summarized, and different treatment methods were used to activate the brain language area. Improving the function of semantic system provides an effective treatment for the recovery of semantic function in aphasia.At the same time,the clinical application of acoustic technology combined with traditional speech therapy and rehabilitation was  described  in practice. Acoustic  software was used to  analyze  acoustic parameters, determine the position  of the lips  and  tongue, and  the  characteristics  of  speech  and  sound  quality. Clinical  problems  were  analyzed  individually, aiming to provide new treatment methods and methods for semantic treatment of aphasic patients after stroke.

Objective   To investigate the detection of thyroid nodules in helicopter operators and to analyze the potential factors influencing the occurrence of thyroid nodules.Methods   A retrospective analysis was conducted on the medical records and physical examination reports of helicopter operators admitted to a center from August to December 2023.Statistical analysis was performed on the detection of thyroid nodules and related factors.Results   Among 223 helicopter operators,a total of 55 cases of thyroid nodules were detected,resulting in a detection rate of 24.66%.Bilateral lobes (52.73%) were the dominant site of detected thyroid nodules,followed by the right lobe (25.45%),and left lobe (21.82%).The majority of detected nodules were classified as thyroid imaging reporting and data system (TI-RADS) 2 and 3.Multivariate Logistic regression analysis indicated that,with the presence of thyroid nodules as the dependent variable and mean corpuscular hemoglobin(MCH),mean corpuscular volume(MCV),red blood cells(RBC),red blood cell volume distribution width(RDW),and anti-thyroglobulin antibody(TGAb) as covariates,the adjusted odds ratio(OR) for RBC was 0.320 (95% CI:0.115,0.850,P<0.05),showing a significant difference.This suggested that higher levels of RBC were negatively correlated with the risk of developing thyroid nodules.Conclusion   The detection rate of thyroid nodules is relatively high among helicopter operators,with the highest occurrence in bilateral lobes.Multivariate Logistic regression analysis revealed that a decrease in RBC levels is associated with the presence of thyroid nodules.This indicates a potential important role of RBC in the pathogenesis of thyroid nodules.Future research can validate this association,explore the role of RBC in the pathogenesis of thyroid nodules,provide more accurate predictive factors and treatment targets,and reduce the risk of related diseases.

Objective   To  compare and analyze the application effect difference of super-articular external fixation and  locking  compression  plates(LCP) +minimally   invasive  percutaneous  plate   osteosynthesis(MIPPO)   in  treating elderly  patients  with  Gustilo  type  II  open  distal  tibial  fracture. Methods   According  to  the  random  number  table method,76 elderly patients with Gustilo type II open distal tibial fracture treated in Guangxin District People's Hospital from January 2020 to October 2023 were divided into a control group(n=38) receiving super-articular external fixation treatment and a study group(n=38) receiving LCP+MIPPO operation treatment.The surgical indexes,hemodynamics of affected  limb, ankle joint  function  and  clinical  efficacy  of  the  two  groups  were  compared. Results    The  time  of operation,fracture healing and swelling elimination in the study group was lower than that in the control group(r<0.05), and there was no significant difference in the amount of intraoperative blood loss(r>0.05).On day  1 after surgery,the peak systolic blood flow velocity and average blood flow velocity of dorsalis pedis in both groups were higher than before surgery, and the study group was higher than the control group(r<0.05);the resistance index of dorsalis pedis in both groups was lower than before surgery, and the study group was lower than the control group(r<0.05). Three months  after  surgery, the  scores  of Baird-Jackson  ankle joint  function  scale  in  both  groups  were  higher  than  those before surgery, and those in the study group were higher than those in the control group(r<0.05). Three months after operation,the total effective rate of the study group was 97.37%,which was higher than that of the control group(78.95%), r<0.05. Conclusion   Compared with  super-articular external fixation,LCP+MIPPO method can shorten the operative time of elderly patients with Gustilo type II open distal tibial fracture,improve postoperative hemodynamics of dorsal foot  artery, and  contribute  to  the  healing  of  fracture  and  improvement  of  ankle joint  function, and  have  a  positive effect on the improvement of clinical efficacy.

With the rapid development of information technology,the informatization and intelligent construction of convalescent centers have become the key to improve service quality and work efficiency.This paper deeply analyzes the  main  problems  faced  by  the  current  convalescent  centers  in  the  process  of  intelligent  construction, such  as insufficient intelligent support capacity,intelligent application system having not yet formed and intelligent technology promotion bottleneck.In response to these problems,the paper discusses the collaborative application and development status  of cutting-edge technologies  such  as  artificial  intelligence, cloud  computing  and  big  data  in  the  convalescent center, and puts forward the solution of building the intelligent convalescent application architecture. The architecture aims   to   solve   specific   problems   in   convalescent   management,  diagnosis   and   treatment   and    service   quality improvement through the  comprehensive use  of cloud  computing, big  data  and  artificial  intelligence technology, and realize the automation,intelligence and personalized service of convalescent center work.The paper also elaborates the implementation  principle  and  technical  route  of  the  intelligent  recuperation, which  provides  theoretical  basis  and practical guidance for the intelligent transformation of the convalescent center.

Objective   To  observe  the  effect  of transcutaneous  electrical  stimulation  of the  ear  branch  of vagus nerve combined with virtual scenario training on upper limb function in patients with cerebral infarction.Methods  A total of 116 cerebral infarction patients in the recovery period admitted to the Rehabilitation Department of Luoyang Hospital,Dongzhimen Hospital,Beijing University of Chinese Medicine from May 2021 to March 2024 were selected as the  study population. They were  divided  into the virtual  group  and  electrical  stimulation  group using the  lottery method, with  58  cases  per  group. Conventional  secondary  prevention  drugs  for  cerebral  infarction  and  conventional rehabilitation training were  given  in both  groups. Virtual  scenario training  intervention was  conducted in the virtual group, and  transcutaneous  electrical  stimulation  of  the  ear  branch  of  vagus  nerve  was  performed  in  the  electrical stimulation  group. The  surface  electromyographic  signals  of  different  muscle  groups  on  the  affected  side, the  grip strength  of the  affected  side, the  tapping  test  of the  index  finger  on  the  affected  side, the  modified Ashworth  scale (MAS),the Fugl-Meyer assessment(FMA) of motor recovery score of the upper extremity,the Wolf motor function test (WMFT) score of the upper extremity,the modified Barthel index(MBI),the National Institutes of Health  stroke  scale (NIHSS)  score  of  the  upper  extremity, and  the   stroke  specialised  quality  of  life   scale(SS-QOL)  were  compared between  groups  before  and  after  the  intervention. Results   Surface  EMG  signals  of biceps  brachii, triceps  brachii, radial wrist extensors, and radial wrist flexors were significantly elevated in both groups after intervention compared to pre-intervention values,which were significantly higher in the electrical stimulation group than the virtual group(r<0.05). Compared with pre-intervention,the grip strength of the affected hand and index finger tapping test were significantly elevated in both groups after intervention,which were significantly higher in the electrical stimulation group than the virtual group(r<0.05).Compared with pre-intervention values,the MAS grading significantly improved in both groups after intervention,and the improvement was more obvious in the electrical stimulation group(r<0.05).Compared with the pre-intervention  values, the upper  limb  FMA score, MBI  score, SS-QOL  score, and  upper  limb WMFT  score significantly   increased   in  both   groups   after  intervention, which  were   significantly  higher  in  the   electrical stimulation group(r<0.05). The NIHSS score significantly decreased in both groups after intervention,which was significantly  lower  in  the  electrical  stimulation  group  than  the  virtual  group([6.34± 1.07]points  VS  [8.52± 1.46] points,r<0.05).Conclusion   Transcutaneous electrical stimulation of the ear branch of the vagus nerve combined with  virtual  scenario  training  improves  upper  limb  muscle  tone  and  promotes  recovery  of  upper  limb  motor function in patients with cerebral infarction.

Objective   To understand the incidence and risk factors of dyslipidemia in young and middle-aged men in a certain unit, so as to provide reference  for its prevention and intervention. Methods   The  physical  examination data  of young  and  middle-aged  men  in  a  certain  unit  coming  to  a  convalescent  institution  for  recuperation  from January 2019 to December 2020 were collected.The distribution characteristics of the detection rate of dyslipidemia were  analyzed  by  χ2   test, and  the  risk  factors  of dyslipidemia  were  analyzed  by  multi-factor  Logistics  regression. Results   In 956 young and middle-aged men,209 cases were detected with dyslipidemia,the detection rate was 21.9%. The  detection  rates  of  hypercholesterolemia, hypertriglyceridemia, high-low  density  lipoprotein  cholesterol(LDL-C) and  low-high  density  lipoprotein  cholesterol(HDL-C) were  6. 1%, 12.4%, 0.4%  and  10.4%, respectively. Dyslipidemia increased with age(P<0.05).With the increase of body mass index(BMI),the detection rate of dyslipidemia increased (P<0.05). The results  of multi-factor Logistics regression  analysis  showed that  age(OR= 1.047, 95%CI:  1.017, 1.078), overweight(OR=2.208, 95%CI:  1.506, 3.238), obesity(OR=4. 121, 95%CI:  2.032, 8.355), abnormal  alanine  transaminase (ALT) (OR=2.353, 95%CI: 1.568, 3.530), fatty  liver(OR= 1.674, 95%CI:   1. 116, 2.511)  and  hyperuricemia(OR=2.468, 95%CI:1.733, 3.515) were risk factors for dyslipidemia(P<0.05). Conclusion   Age,overweight,obesity, abnormal ALT, fatty liver and hyperuricemia are all risk factors for dyslipidemia in young and middle-aged men. Except age, other factors are related to poor diet and lifestyle habits. Therefore,reducing the intake of fat and purine and scientifically exercising to control BMI are effective measures to prevent and intervene in dyslipidemia.

Objective To investigate the impacts of folic acid on the levels of superoxide dismutase(SOD),glutathione peroxidase(GSH-Px), glutathione(GSH), and malondialdehyde(MDA) in non-alcoholic fatty liver disease(NAFLD) rats. Methods Sprague-Dawley(SD) rats were fed with high-fat diet for 8 weeks to construct a NAFLD model.They were randomly separated into the model group,low-dose folic acid group(10 mg/kg),medium-dose folic acid group(20 mg/kg),high-dose folic acid group(40 mg/kg),and Orlistat group(60 mg/kg positive control drug),with 10 rats in each group.Another 10 SD rats were fed with normal diet for 8 weeks were included as the control group.After treatment with folic acid and Orlistat,the levels of total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),triglyceride(TG),and free fatty acid(FFA) in rat blood lipids,and liver function indicators like alanine aminotransferase(ALT), γ-glutamyl transpeptidase(γ-GT), and aspartate aminotransferase(AST) were detected. H&E staining and Oil Red O staining were respectively applied to detect the morphology and steatosis of rat liver tissue. The NAFLD activity scores of each group were compared.Reagent kits were applied to detect the levels of SOD,GSH-Px,GSH,and MDA in rat serum and liver tissue. Results Compared with those of the control group, rats in the model group showed obvious steatosis and pathological damage in the liver, significantly higher serum levels of TC, LDL-C, TG,FFA,ALT,γ-GT and AST,NAFLD activity score,and MDA in serum and liver tissue,but significantly lower SOD,GSH-Px,and GSH in serum and liver tissue(P<0.05).Compared with those of the model group,rats in the low,medium,high-dose folic acid groups had reduced steatosis and pathological damage in the liver tissue, significantly lower serum levels of TC, LDL-C, TG, FFA, ALT, γ-GT and AST, NAFLD activity score, and MDA in serum and liver tissue, but significantly higher SOD,GSH-Px,and GSH in serum and liver tissue in a dose-dependent manner(P<0.05).Compared with the highdose folic acid group, all indicators were similar to the Orlistat group(P>0.05). Conclusion Folic acid can reduce blood lipid levels, enhance antioxidant enzyme activity, lower lipid peroxidation levels, and inhibit oxidative stress in NAFLD rats,thereby reducing hepatic steatosis,pathological damage,and improving liver function in rats.

Objective    To    evaluate   the   incidence    of   frailty   in   elderly    outpatients   in   community   by   the comprehensive  geriatric  assessment(CGA)  and  to  analyze  its  influencing  factors. Methods    From  January  2022  to December 2022, totally 279 elderly out patients in community visited the health  service center in  Shinan District of Qingdao  were  selected  as  the  study  objects. The  frailty  was  assessed  by  the  Fried  frailty  phenotype(FFP). All  the subjects  were  comprehensively  evaluated  by  CGA  for  physical  function  status, nutritional   status, mental  status, sarcopenia, comorbidity, multiple  drug  use  and  sleep  status. Laboratory  indicators, such  as  hemoglobin(Hb), albumin (ALB),blood lipids and hypersensitive C-reactive protein(hs-CRP) were collected to analyze the relationship between frailty and clinical data. Results  Among the 279 subjects,51 cases( 18.28%) were in the frailty group,89 cases(31.90%) were  in the pre-frailty  group, and  139  cases(49.82%)  were  in the non-frailty  group. Univariate  analysis  showed that age, sex, marital  status, smoking  status, activities  of daily  life(ADL), the  Tinetti  score, the  mini  nutritional  assessment short-form(MNA-SF)   score,  the   mini-mental    state   examination(MMSE)    score,  geriatric   depression,  sarcopenia, comorbidity,multiple drug use,total serum protein,ALB,Hb,high-density lipoprotein,hs-CRP, and blood calcium levels were significantly different among the three groups(r<0.05).Ordered logistic regression analysis showed that age,sex, smoking, malnutrition, number  of comorbidities, total  serum protein, Hb  and hs-CRP were the  influencing  factors  for frailty(r<0.05). Conclusion   Nearly  half of the  elderly  outpatients in  community  are  frailty  and pre-frailty. CGA in the elderly can be used to screen frailty and pre-frailty early,and can be intervene in comorbidities management and nutritional support,so as to improve the quality of life of the elderly.