Objective To investigate and study the application and evaluation of natural convalescent factors in the rehabilitation institutions of health resorts in China,in order to provide scientific basis for the scientific planning,rational development,utilization,and protection of medical natural resources in the rehabilitation institutions of health resorts.Methods The random cluster sampling method was adopted to conduct a survey on 70 rehabilitation institutions across the country from May to August 2024.68 valid institution samples were collected.SPSS AU 27.0 software was used to analyze and evaluate the nature of different natural convalescent factors and the application and suitability of medical natural resources.Results The evaluation of 34 sea bathing beaches showed that 70.6% had clear water,while 29.4% had turbid water;58.8% were safe without any danger,and 38.3% had a slight danger;58.8% had slightly turbid seawater color;73.5% of the 1.5-meter-deep water area (distance from the coastline) was >30.5 meters;73.5% of the beaches had good conditions.The evaluation of 30 sunbathing beaches showed that 80.0% of the beaches had an area per person >4.5 m2,60.0% of the beaches free from intense sun exposure throughout the year were >80%,76.7% of the beaches had backland cover and trees,and 86.7% of the beaches had waste and natural hazard substances.The evaluation of 23 mineral water resources showed that 47.8% of the mineral water had an outlet temperature ≥50 ℃ and <70 ℃;52.1% contained two or more trace elements,gases,and radioactive elements,and had a mineralization degree ≥1 g/L;95.7% of the mineral water met the GB 8537 standard,and only one health resort did not meet the sewage comprehensive discharge standard;56.6% of the mineral water had daily hygiene routine tests and had full-time testing personnel;52.1% of the mineral water was applied in medical fields.The evaluation of 9 mud therapy resources showed 44.4% of the mineral salts was ≤10%,and 55.6% had temperatures ≥42 ℃ and <55 ℃;44.5% of the application methods (full-body immersion,local wrapping,mud paste,adding Chinese medicine,electricity,wax,etc.) involved more than 3 types;Only 2 of the health resorts failed to meet the mud quality and microbial indicators standards;44.4% of the health resorts were used for medical and health care.The evaluation of 29 forest bathing resources showed 89.6% located more than 20 km away from industrial areas or urban noisy zones,being mountain forests with convenient transportation,fresh air and no noise;82.8% of the forest land had trails,with more than 2 types of design,and the forest was comfortable for walking and activities;62.1% had an area of over 670 hectares;93.1% had a vegetation quantity that maintained green landscapes and seasonal changes;79.3% had certain tree species that could volatilize a large number of aromatic substances.Conclusion It is necessary to regularly assess the quantity,quality,distribution of natural convalescent factors in the health resorts,and analyse its convalescent value,strictly follow the ecological environment safety and health care parameters.Relying on policy-driven and international certification standards,it is to promote the scientific application and sustainable development of natural convalescent factors in the rehabilitation institutions of health resorts,and contribute to Healthy China.
Objective To systematically evaluate the incidence rate of comprehensive fatigue among Chinese military officers and soldiers and explore its development trend.Methods The Chinese databases were retrieved,the Excel was used to manage and screen the literature,and the quality was evaluated according to the cross-sectional study evaluation criteria of the US Agency for Healthcare Research and Quality(AHRQ).The evaluation was independently conducted by two researchers.The StataMP 18.0 software was adopted for the analysis.Results After analyzing 26 studies involving 21 955 military officers and soldiers,there were 7,008 cases of fatigue.The the overall incidence rate by random effects models weighted aggregation was 29.8%(95%CI:25.7%-34.5%),and it showed a fluctuating upward trend from 2011 to 2025.The incidence rate among naval officers and soldiers was the highest.There were differences in the results of different assessment tools,and the meta-regression indicated that the work on ships had a significant positive effect on the effect size.Conclusion The incidence rate of fatigue and chronic fatigue syndrome among our military officers and soldiers is high.The condition of the naval officers and soldiers is worrying.Fatigue is likely related to the mind.Most assessment tools are subjective evaluations.In the future,it is necessary to explore objective indicators and develop specific scales.
Objective To analyze the current research status of ferroptosis and osteoporosis with CiteSpace,to explore the research hotspots and trends,and provide theoretical references for subsequent related studies.Methods A systematic search was conducted on the Web of Science (WOS) core database,with the time limit set from January 1,2012 to September 12,2025,for relevant research literature published during this period.The CiteSpace 6.3.R1 software was used to conduct a visual analysis of the keywords,authors,institutions,etc.of the included literature.Results A total of 174 articles were included.The author with the highest number of research publications was Zhang Jian;a collaboration network centered around Zhang Jian and Wang Peng was formed.The research institution with the most publications was Zhejiang University,and a cooperative group of institutions with Shanghai Jiao Tong University as the core emerged.The frequently used keywords indicated that the research mainly focused on Oxidative Stress,Cell Death,Differentiation,etc.;in terms of the evolution of research trends,iron metabolism,osteoclast differentiation,and specific bone diseases have become the current research priorities.Conclusion At present,the research on ferroptosis and osteoporosis is experiencing a continuous increase in popularity year by year.There is close collaboration among various scholars and institutions,and extensive basic mechanism research is being carried out.The exploration of intervention strategies is currently a relatively active direction.
Objective To explore the current situation,hotspots,and development trends of continuous care for diabetic in China based on CiteSpace.Methods The three databases of China National Knowledge Infrastructure(CNKI),VIP Database,and Wanfang Data Knowledge Service Platform were searched.The relevant studies on continuous care for diabetes in China were collected.The search time limit was from January 1,2015 to July 1,2025.The search and analysis were conducted with the CiteSpace 6.4.R1 software and the knowledge map was drawn.Results A total of 2 906 articles were included.The main institutions were universities and their affiliated hospitals.The key words focused on quality of life,diabetic foot,etc.The keywords formed 12 clusters including quality of life,diabetic foot,self-management,etc.The keyword with the highest prominence was sleep quality.Conclusion Based on the number of published papers over the past 10 years,the research on continuous care for diabetic in China has entered a stable development stage.However,there are issues such as weak collaboration among institutions and a lack of cost-effectiveness evaluation.In the future,it is necessary to strengthen cross-institutional and international cooperation,promote the standardization of care plans,in order to improve the continuous care system for diabetes and improve the prognosis of patients.
Objective To explore the effects of governor vessel circulation and warming kidney moxibustion on inflammatory factor levels and bone metabolism indicators in patients with ankylosing spondylitis of kidney deficiency and governor vessel cold type.Methods A total of 108 patients with ankylosing spondylitis of kidney deficiency and governor vessel cold type admitted to Henan Provincial Hospital of Integrated Traditional Chinese and Western Medicine from May 2024 to May 2025 were selected as the research subjects.They were divided into groups according to the random number table.54 patients in the control group received conventional treatment (rehabilitation training+Western medicine),while 54 patients in the observation group received additional treatment of governor vessel circulation and warming kidney moxibustion.The traditional Chinese medicine syndrome scores,disease activity,spinal function,inflammatory factor levels,and bone metabolism indicators of the two groups of patients were compared.Results The scores of cold pain in the lumbar and sacral regions,morning stiffness,difficulty in bending and turning,aversion to cold and cold extremities,soreness in the waist and knees,lack of energy,clear and long urine,frequent nocturnal urination in the observation group were all lower than those in the control group(P<0.05);the Bath Ankylosing Spondylitis Disease Activity Index(BASDAI) and Bath Ankylosing Spondylitis Functional Index(BASFI) scores of the observation group were both lower than those of the control group(P<0.05);the levels of tumor necrosis factor-α(TNF-α),interleukin-1β (IL-1β),C-reactive protein(CRP),and receptor activator of nuclear factor-κB ligand (RANKL) in the observation group were all lower than those in the control group(P<0.05);the levels of C-terminal telopeptide of type Ⅰ collagen(CTX-Ⅰ) and tartrate-resistant acid phosphatase(TRACP) in the observation group were both lower than those in the control group,while the level of bone gla protein(BGP) was higher than that in the control group(P<0.05).Conclusion Governor vessel circulation and warming kidney moxibustion can effectively alleviate the symptoms of patients with ankylosing spondylitis,reduce the disease activity,enhance spinal function,and improve bone metabolism levels and inflammatory responses.
Objective To explore the intervention effect of ear acupoint Guasha combined with Kaitianmen therapy on people with sleep disorders.Methods 92 patients with sleep disorders admitted to the Preventive Treatment Department of Ganzhou Traditional Chinese Medicine Hospital from January 2024 to June 2025 were divided into a control group and an experimental group according to the random number table,with 46 cases in each group.Both groups received routine nursing measures.On this basis,the control group received intervention with Kaitianmen therapy,while the experimental group received intervention with ear acupoint Guasha combined with Kaitianmen therapy,for a period of 4 weeks.The intervention effects of the two groups were compared.The scores of the Spiegel Sleep Questionnaire(SPIEGEL) and Fatigue Scale-14 (FS-14) between the two groups before intervention and after 4 weeks of intervention were compared;And the occurrence of adverse reactions was recorded.Results Compared with the control group (78.26%),the total effective rate of intervention in the experimental group (93.48%) was much higher (P<0.05).At 4 weeks of intervention,the SPIEGEL scores and FS-14 scores of both groups decreased,and those of the experimental group were lower than those of the control group (P<0.05).There was no difference of statistical significance in the incidence of adverse reactions between the two groups (P>0.05).Conclusion The application of ear acupoint Guasha combined with Kaitianmen therapy in people with sleep disorders can improve their sleep quality,reduce fatigue,and bears certain safety.
Objective To explore the application effect of hyperbaric oxygen combined with dual-task training in the rehabilitation treatment of patients with post-stroke cognitive impairment (PSCI).Methods A total of 104 PSCI patients admitted to Wuxi Rehabilitation Hospital from March to October 2025 were selected and divided into two groups according to the random number table.Both groups received routine intervention management.52 patients in the control group received dual-task training treatment,while 52 patients in the observation group and received hyperbaric oxygen combined with dual-task training.Both groups received treatment for 30 days.The data of limb function (Fugl-Meyer Assessment of Upper Extremity Function [FMA-UE],Berg Balance Scale [BBS]),cognitive function (Montreal Cognitive Assessment Scale [MoCA],Mini-Mental State Examination Scale [MMSE]),modified Barthel Index (MBI),and adverse reactions before treatment and on the 30th day of treatment were compared between the two groups.Results On the 30th day of treatment,compared with before treatment,the scores of FMA-UE,BBS,MMSE,MoCA and MBI in both groups increased,and compared with the control group,the above scores in the observation group were higher ([34.20±5.10] points VS [31.46±5.35] points,[33.25±3.75] points VS [31.10±4.30] points,[26.10±1.10] points VS [23.75±1.04] points,[22.35±1.68] points VS [19.40±2.02] points,[84.40±3.20] points VS [81.20±4.15] points,P<0.05).Conclusion Hyperbaric oxygen combined with dual-task training can improve the limb function and cognitive function of patients with PSCI,as well as enhance their activities of daily living.
Objective To explore the effect of occupational therapy combined with repetitive transcranial magnetic stimulation (rTMS) on the functional independence of patients with dyskinesia after incomplete spinal cord injury.Methods A total of 104 patients with incomplete spinal cord injury and dyskinesia who were admitted to Shangqiu Hospital of Traditional Chinese Medicine from June 2023 to June 2025 were selected.They were divided into an observation group (occupational therapy combined with rTMS therapy) and a control group (rTMS therapy) according to the random number table,with 52 cases in each group.The changes in functional independence,functional recovery,sensory function,quality of life,and the incidence of complications before and after treatment were compared between the two groups.Results After the intervention,the scores of each dimension of functional independence in the observation group (self-care [16.02±2.08] points,swallowing and breathing [7.49±0.97] points,mobility [34.72±3.34]points,and sphincter management [24.91±2.37] points) were all higher than those in the control group ([14.19±2.11]points,[6.85±0.93] points,[32.61±3.20] points,and [22.01±2.28] points),P<0.05;after the intervention,the balance ability (43.16±5.03) points,lower limb movement (40.21±5.44) points,and exercise endurance (376.15±29.86) points in the observation group were all higher than those in the control group ([39.72±5.28] points,[36.05±5.27] points,and [352.44±30.10] points) (P<0.05);After the intervention,the sensory function scores of the left and right sides in the observation group ([95.52±7.66] points,[96.40±7.09] points) were higher than those in the control group ([88.75±7.42] points,[88.11±7.81] points) (P<0.05);after the intervention,the scores of each dimension of the quality of life in the observation group (physiological [86.22±7.12] points,psychological [83.25±7.68] points,social relationship [85.27±7.10] points,and environment [86.27±6.38] points) were higher than those in the control group ([81.04±7.30] points,[77.64±8.11] points,[80.33±7.68] points,and [80.16±6.64] points) (P<0.05);there was no difference of statistical significance in the comparison of complications between the two groups (P>0.05).Conclusion Occupational therapy combined with rTMS therapy for treating dyskinesia after incomplete spinal cord injury can help improve patients' functional independence,promote functional recovery,enhance sensory function,improve the quality of life,and has high safety.
Objective To explore the effects of Ningzhi capsules combined with Baduanjin on the sleep and quality of life of hemodialysis patients.Methods Sixty insomnia patients who underwent regular hemodialysis in the hemodialysis room of Pingxiang Traditional Chinese Medicine Hospital from March 2023 to March 2025 were selected as the research subjects.They were divided into a control group and an observation group according to the random number table,with 30 cases in each group.The control group was treated with alprazolam,while the observation group was treated with Ningzhi capsules combined with Baduanjin.Both groups were treated for 3 months,during which no samples were dropped.The clinical efficacy,Pittsburgh Sleep Quality Index (PSQI),Kidney Disease Quality of Life(KDQ),Minnesota Living with Heart Failure Questionnaire(MLHFQ),and adverse reactions between two groups before and after treatment were compared.Results The clinical efficacy of the observation group (86.67%) was significantly higher than that of the control group (63.33%) (P<0.05).The scores of each dimension and the total score of PSQI in the observation group after treatment were lower than those in the control group (all P<0.05).The KDQ score in the observation group after treatment (142.67±11.01) points was higher than that in the control group (130.57±10.21) points;the MLHFQ score (27.13±3.18) points in the observation group was lower than that in the control group (32.10±3.50) points (all P<0.05).There was no difference of statistical significance in the adverse reaction situations between the control group 16.67% and the observation group 23.33% (P>0.05).Conclusion The efficacy of Ningzhi capsules combined with Baduanjin in treating insomnia in patients undergoing regular hemodialysis is superior to that of conventional Western medicine treatment.It can improve the sleep quality and quality of life of these patients.
Objective To explore the effects of Tai Chi imagery therapy combined with intermittent load training on patients after percutaneous coronary intervention (PCI).Methods 120 patients with coronary heart disease who underwent PCI treatment at Tianjin Chest Hospital from September 2023 to September 2025 were divided into a control group (receiving routine rehabilitation care) and a study group (receiving Tai Chi imagery therapy and intermittent load training in addition to the routine rehabilitation care) according to the random number table,with 60 cases in each group.The intervention lasted for 8 weeks.The levels of kinesiophobia,psychological state scores,and cardiac function indicators before and after the intervention were compared between the two groups.Results After the intervention,the total score of the Tampa Scale for kinesiophobia Heart (TSK-SV Heart) was (26.64±2.75) points,the scores of the Self-Rating Anxiety Scale (SAS) and the Self-Rating Depression Scale (SDS) were (37.75±2.41) points and (35.47±2.68) points respectively in the study group,all of which were lower than those of the control group (29.32±3.31) points,(39.46±2.90) points and (37.10±2.63) points.The left ventricular ejection fraction (LVEF) was (59.14±2.78)%,which was higher than that of the control group (56.58±2.69)%,while the left ventricular end-diastolic diameter (LVEDD) and the N-terminal pro-B-type natriuretic peptide (NT-proBNP) level were (51.14±2.61) mm and (187.19±12.36) pg/mL respectively,both of which were lower than those of the control group (53.27±3.11) mm and (202.42±21.27) pg/mL (P<0.05).Conclusion Tai Chi imagery therapy combined with intermittent load training can reduce kinesiophobia in patients after PCI,alleviate anxiety and depression,and improve cardiac function.
Objective To evaluate the effects of mechanical dynamic traction combined with conventional rehabilitation exercises on ankle-hindfoot function and six‑degree‑of‑freedom motion parameters in patients after pronation-external rotation(PER) ankle fracture surgery.Methods From January 2024 to May 2025,105 postoperative PER ankle fracture patients treated at Zhengzhou Orthopaedic Hospital were enrolled and randomly assigned by lottery to a control group (n=52) or a study group (n=53).The control group received conventional rehabilitation exercises;the study group received the same rehabilitation plus mechanical dynamic traction therapy.Outcome measures included six‑degree‑of‑freedom motion parameters,ankle-hindfoot function,quality of life,and complication rates.Results Postoperatively,the study group scored higher than the control group on all domains of the general quality of life inventory‑74 (GQOLI‑74) (P<0.05).The study group's Olerud-Molander ankle score (OMAS) and American orthopedic foot and ankle society (AOFAS) ankle-hindfoot score were (85.11±6.02) and (90.17±8.03),respectively,both significantly higher than the control group's scores of (61.58±5.32) and (64.02±5.80)(t =21.208 and 19.755,P<0.05).The study group demonstrated greater degrees of internal/external rotation,plantarflexion/dorsiflexion,and inversion/eversion than the control group (P<0.05).In contrast,superior/inferior,medial/lateral,and anterior/posterior translation distances were smaller in the study group than in the control group (P<0.05).The complication rate in the study group (1.89%) was significantly lower than that in the control group (13.46%) (χ2=4.996,P<0.05).Conclusion In patients after PER ankle fracture surgery,adding mechanical dynamic traction to conventional rehabilitation effectively optimizes six‑degree‑of‑freedom motion parameters,improves ankle-hindfoot function and quality of life,and reduces the incidence of complications.
Objective To optimize a multimodal sensory stimulation protocol for arousal-promoting nursing care in neurosurgical comatose patients and to assess its clinical effectiveness.Methods One hundred neurosurgical comatose patients admitted to Quanzhou First Hospital,Fujian,between January 2024 and September 2025 were randomized (random number table) into two groups of 50.The study group received a multimodal sensory stimulation protocol-incorporating visual,auditory,tactile,and olfactory stimuli-with dynamic adjustments to stimulus intensity,frequency,and timing tailored to each patient's condition and individual characteristics. The control group received a fixed-pattern sensory stimulation regimen.Primary and secondary outcomes included Glasgow coma scale (GCS) scores,incidence of complications,and quantitative electroencephalography (qEEG) parameters.Results Baseline GCS and other measures did not differ significantly between groups (P>0.05).Following the intervention,the study group demonstrated a higher mean GCS score (12.52±1.82) than the control group (10.13±2.35),P<0.05.The study group's complication rate was 2%,compared with 14% in the control group (P<0.05).qEEG analysis showed a higher awakening index in the study group (30.54±3.43) than in the control group (24.24±2.85) after intervention (P<0.05).Conclusion An individualized,dynamically adjusted multimodal sensory stimulation protocol significantly enhances arousal in neurosurgical comatose patients.
This article systematically reviews Chinese and international research on loneliness among primary caregivers of disabled older adults in rural settings.Beginning with definitions and relevant theoretical frameworks of loneliness,it summarizes the prevalence and adverse physical and mental health effects of caregiver loneliness,and analyzes the mechanisms through which sociodemographic factors,social support,and caregiving burden influence loneliness.The review also synthesizes current evidence and implementation status for interventions such as mindfulness meditation,peer-support programs,and the comprehensive health enhancement support system (CHESS).Findings indicate that loneliness is widespread in this caregiver population and is closely associated with depression,anxiety,sleep disturbances,and elevated risk of chronic disease;inadequate social support and excessive caregiving burden are identified as core determinants.Research and intervention efforts specifically targeting caregivers of rural disabled older adults remain limited,with notable gaps in large-sample quantitative studies and culturally tailored intervention models.Future work should strengthen systematic assessment of caregiver loneliness,improve rural eldercare services and support systems,and develop integrated,context-appropriate interventions to protect caregivers'physical and mental health and to enhance the quality of care.
Motoric cognitive risk (MCR) syndrome is a common pre‑dementia condition in older adults,defined primarily by slow gait and subjective cognitive decline.Its onset is associated with advanced age,unhealthy lifestyle factors,and chronic diseases.Clinically,MCR is often insidious but serves as an effective predictor of adverse outcomes such as dementia,falls,disability,and mortality,representing a key transitional stage between normal aging and dementia.The prevalence of MCR among older adults in China is relatively high and increases with age.Although research on MCR has progressed and several screening tools have been preliminarily introduced in clinical practice,important challenges remain: diagnostic criteria are not yet standardized and vary between studies,the underlying pathophysiological mechanisms are not fully clarified,and existing intervention programs lack robust,localized evidence tailored to the characteristics of China's elderly population.This review focuses on both clinical and basic research into MCR,systematically summarizing its core features,epidemiology,predictive value,risk factors,and intervention strategies,and synthesizing recent advances and current practice.Our goal is to elucidate the etiological connections and intervention priorities for MCR,providing a theoretical foundation to improve early identification processes and to develop precision,context‑appropriate interventions for China's older population,thereby reducing dementia risk and promoting healthy aging.
Obsessive-compulsive disorder (OCD) is a stubborn clinical problem encountered both in mental-health services and school counseling systems,and it remains a fertile area for further research.This paper reviews the concept and prevalence of OCD,summarizes debates about its etiology,and evaluates the current status and outcomes of psychological interventions.It highlights key dilemmas in contemporary research and practice: studies tend to be outcome‑oriented rather than process‑oriented,and the causal relationships between clinical symptoms and observed neurophysiological abnormalities remain unclear;empirical,localized investigations of psychotherapeutic effects are inadequate,and reported benefits are often limited to statistically significant changes on rating scales rather than demonstrable functional or neurobiological improvements.To advance the field,we recommend developing integrative,group‑based psychotherapeutic programs for OCD with long‑term outcome tracking,and strengthening neurobiological research aimed both at clarifying causal links between neural changes and symptoms and at rigorously testing whether psychological treatments can induce measurable,reversible neurophysiological changes in individuals to help bolster patients' treatment confidence and adherence.
Knee osteoarthritis(KOA) is a chronic degenerative joint disorder that substantially impairs quality of life.Recently,external applications of Chinese herbal medicine, such as fumigation-and-washing,hot compresses,and poultices,together with exercise-based therapies including Taichi boxing,Baduanjin,and targeted functional exercises,have gained attention as safe,environmentally friendly,simple,and cost‑effective noninvasive options.Current evidence indicates that exercise therapies are primarily applied for early-stage management and subsequent rehabilitation of KOA,whereas topical herbal treatments are more commonly used during the mid stage.Combined use of topical Chinese medicine and exercise therapy is frequent in clinical practice and appears to exert multiple beneficial effects: suppression of inflammatory mediators,removal or neutralization of pain‑related substances,enhancement of local blood circulation,alleviation of joint stiffness and swelling‑associated pain,restoration of joint function,improvement in mobility,and reduction of systemic drug-related adverse effects.These combined approaches are therefore suitable for treating early to mid‑stage KOA.This review synthesizes recent clinical and mechanistic studies on the combination of topical Chinese medicine and exercise therapy for KOA to inform future research and clinical practice.
Objective To design a lifestyle-medicine health-management system specifically adapted to rehabilitation and convalescence centers,refine intervention models for people with chronic disease,suboptimal health,postoperative recovery,and elderly convalescents,and thereby elevate service quality and health-management performance.Methods Anchored in the health-management cycle concept and a multidisciplinary collaboration model,we combined literature review,experiential synthesis,process reengineering,and indicator-system development to define practical application pathways,key implementation elements,outcome evaluation metrics,and optimization strategies for applying lifestyle medicine in rehabilitation and convalescence settings.Results We implemented a site-specific program structured around six core pillars-nutrition,physical activity,sleep optimization,stress management,correction of unhealthy behaviors,and social support-and created a multidimensional evaluation framework covering physiological measures,lifestyle behaviors,psychological state,quality of life,and convalescence-management indicators.Application of this framework led to measurable improvements in physiological parameters including blood pressure,blood glucose,and blood lipids;facilitated correction of unhealthy habits;and improved both physical and mental well-being and satisfaction with convalescence services.Conclusion Integrating lifestyle medicine into rehabilitation and convalescence health management complements and strengthens traditional models by shifting focus from symptomatic relief to upstream,root-cause interventions and from episodic convalescence to sustained health management.This approach carries significant practical value for advancing the high-quality development of rehabilitation and convalescence institutions.
Objective To evaluate the diagnostic value of the electrocardiographic P‑wave terminal force in lead V1(PTFV1),combined with peripheral blood levels of fibronectin type Ⅲ domain‑containing protein 5(FNDC5) and Parkin,in assessing left ventricular diastolic dysfunction(LVDD) in patients with chronic heart failure(CHF).Methods This retrospective study included 256 consecutive CHF patients seen at the First Affiliated Hospital of Henan University from April 2021 to May 2025.Patients were classified by presence of LVDD into a normal diastolic function group(n=184) and a dysfunction group(n=72).Echocardiographic measures recorded included left atrial anteroposterior diameter(LAD),peak filling rate during diastole(PFR),and time from end‑systole to PFR(TPFR).Serum FNDC5 and Parkin concentrations were measured by enzyme-linked immunosorbent assay(ELISA).Pearson correlation assessed relationships among variables.Logistic regression identified independent risk and protective factors for LVDD.Receiver operating characteristic(ROC) curves evaluated diagnostic performance of individual and combined markers;internal validation of the combined model was performed using the bootstrap method and calibration plots.Results Compared with the normal function group,the LVDD group had significantly higher PTFV1,LAD,and TPFR,and significantly lower serum FNDC5,Parkin,and PFR(all P<0.05).In CHF patients,PTFV1 was positively correlated with LAD and TPFR and negatively correlated with PFR;serum FNDC5 and Parkin were negatively correlated with LAD and TPFR and positively correlated with PFR(all P<0.05).Multivariable logistic regression showed PTFV1,LAD,and TPFR were independent risk factors for LVDD,whereas FNDC5,Parkin,and PFR were independent protective factors(P<0.05).Area under the ROC curve(AUC) for predicting LVDD was 0.834 for PTFV1,0.789 for FNDC5,0.781 for Parkin,and 0.945 for the combined model;the combined model's AUC was significantly higher than each single marker(Z=3.447,4.466,4.821;P<0.05).Calibration analysis showed good agreement between predicted and observed probabilities.Conclusion In CHF patients with LVDD,PTFV1 is increased while serum FNDC5 and Parkin are decreased.Combined assessment of PTFV1,FNDC5,and Parkin improves discrimination of LVDD and may help guide clinical management.
Objective To evaluate the clinical effects of low‑temperature plasma radiofrequency ablation combined with low‑frequency pulsed electromagnetic field therapy in patients with lumbar disc herniation.Methods We retrospectively reviewed 80 patients with lumbar disc herniation treated at Putian No.95 Hospital between January and September 2025.Patients were assigned to a control group (n=48) or a study group (n=32) based on the treatment received.The control group underwent conventional surgery plus low‑frequency pulsed electromagnetic field therapy; the study group received low‑temperature plasma radiofrequency ablation combined with low‑frequency pulsed electromagnetic field therapy.The intervention period was two months.Outcomes compared included overall clinical efficacy,pain (visual analogue scale,VAS),lumbar function (Japanese Orthopaedic Association score,JOA),disability (Oswestry Disability Index,ODI),inflammatory markers (interleukin‑6 [IL‑6],interleukin‑8 [IL‑8]),and adverse event rates.Results After treatment,the study group had a higher total effective rate than the control group (86.84% VS 64.29%,P<0.05).The study group showed significantly lower VAS and ODI scores and a higher JOA score compared with the control group (all P<0.05).Serum IL‑6 and IL‑8 levels were significantly lower in the study group than in the control group (both P<0.05).The incidence of adverse reactions was 13.16% in the study group versus 33.33% in the control group(P<0.05).Conclusion In this retrospective cohort,low‑temperature plasma radiofrequency ablation combined with low‑frequency pulsed electromagnetic field therapy was associated with a higher overall clinical effective rate,shorter operative and hospital durations,greater pain relief,improved lumbar function,reduced inflammatory marker levels,and a favorable safety profile.
Objective Using large‑sample survey data,this study characterized the distribution of occupational health knowledge‑attitude‑practice (KAP) among assistant fire station chiefs in China and identified factors associated with high knowledge levels.Methods A cross‑sectional survey was conducted within a national grassroots training program for assistant fire station chiefs.From September 2024 to October 2025,1 575 valid responses were collected via an electronic questionnaire."High knowledge" was defined as the dependent variable;independent variables included demographic characteristics and satisfaction with personal protective equipment(PPE),among others.Data were analyzed with descriptive statistics,χ² tests,multilevel logistic regression,and latent class analysis(LCA).Results The occupational health KAP pattern among assistant fire station chiefs exhibited a "three highs and two lows" profile:high/frequent awareness of obvious risk scenarios,strong recognition of the importance of occupational health,and high adherence to basic protective actions;but low depth of awareness for latent/long‑term risks and low implementation of health management in non‑duty scenarios.Multilevel logistic regression identified bachelor's degree or higher(OR=2.21),≥16 years of service(OR=1.93),and ≥2 training sessions(OR=3.05) as positive predictors of high knowledge,while low PPE satisfaction was negatively associated(OR=0.58).LCA classified participants into three distinct groups:high‑knowledge/high‑demand(27.4%),moderate‑knowledge/equipment‑driven (42.8%),and low‑knowledge/low‑protection(29.8%);these groups differed significantly in education,years of service,and call‑out frequency(P<0.05).Conclusion Knowledge and protective behaviors among assistant fire station chiefs are not fully synchronized.Education level,length of service,training frequency,and PPE quality/satisfaction are key modifiable factors.Targeted optimization of training,equipment provision,and workplace health management is recommended to enhance occupational health protection for this workforce.
Objective To identify factors underlying the practical dilemmas encountered by geriatric specialist clinicians in hospice care and to inform efforts to advance hospice care services.Methods From December 2024 to January 2025,we purposively sampled 14 geriatric specialist medical and nursing staff working in the comprehensive ward of the Cadre Medical Department at a tertiary A hospital in Guizhou Province and at a medical-nursing integrated institution within its medical consortium.Semi‑structured in‑depth interviews were conducted,and the data were analyzed using directed content analysis guided by an implementation framework for integrated care for older adults.Results Analysis yielded three overarching themes and seven subthemes.At the macro level,hospice care practice is constrained by systemic and resource-related barriers(policy,financial and legal dilemmas;structurally inadequate support systems).At the meso level,support networks for horizontal collaboration and vertical continuity are underdeveloped (incomplete multidisciplinary collaboration mechanisms,insufficient intra‑family support,and poor linkage with external continuity-of-care services).At the micro level,service supply is inadequate and poorly matched to individualized needs (communication and decision‑making challenges that lead to deviations from truly patient‑centered care; limited service incentives and insufficient breadth and reach of available programs).Conclusion Geriatric hospice care is limited by factors spanning policy,organizational and individual levels.From an integrated care standpoint,there is an urgent need to develop multi‑stakeholder,integrated hospice care models to address these barriers.
